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Positive Samples: HeLa, HT-29, SKOV3, Mouse liver, Mouse kidney^M
^M
Immunogen sequence: CTQECVSDSE CADNLKCCSA GCATFCSLPN DKEGSCPQVN INFPQLGLCR DQCQVDSQCP GQMKCCRNGC GKVSCVTPNF
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymal protein 4; Epididymal secretory protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core; Major epididymis-specific protein E4; MGC57529; Putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; WAP domain-containing protein HE4; WAP four-disulfide core domain protein 2
Gene Aliases: 1600023A02Rik; dJ461P17.6; EDDM4; HE4; WAP5; WFDC2
UniProt ID: (Human) Q14508, (Mouse) Q9DAU7
Entrez Gene ID: (Human) 10406, (Mouse) 67701
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