This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
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Protein Aliases: MGC111041; Protein PRPL-2; PRPL-2; testicular tissue protein Li 226; WAS/WASL interacting protein family, member 1; WAS/WASL-interacting protein family member 1; WASP-interacting protein; WASPIP; WIP; WIPF1; Wiskott-Aldrich syndrome protein interacting protein; Wiskott-Aldrich syndrome protein-interacting protein
Gene Aliases: PRPL-2; WAS2; WASPIP; WIP; WIPF1
UniProt ID: (Human) O43516
Entrez Gene ID: (Human) 7456