MA5-15502 targets WNT5A in IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15502 immunogen is purified recombinant fragment of WNT5A expressed in E. Coli.
MA5-15502 detects WNT5A which has a predicted molecular weight of approximately 42.3kDa.
Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.
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Protein Aliases: OTTHUMP00000212837; OTTHUMP00000212861; Protein Wnt-5a; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein
Gene Aliases: hWNT5A; WNT5A
UniProt ID: (Human) P41221
Entrez Gene ID: (Human) 7474
Molecular Function: signaling molecule