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Invitrogen
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Monoclonal |
Type |
Antibody |
Clone |
G.307.7 |
Immunogen |
Synthetic peptide corresponding to residues surrounding Glu201 of Isoform 1 and Glu186 of Isoform 2 of the human Wnt5a protein |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
50 µg/mL |
Purification |
Affinity chromatography |
Storage buffer |
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
Contains |
<0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_10986099 |
It is not recommended to aliquot this antibody.
This antibody works to detect both isoforms of human Wnt5a protein.
Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: OTTHUMP00000212837; OTTHUMP00000212861; Protein Wnt-5a; wingless-related MMTV integration site 5A; wingless-type MMTV integration site 5A; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein
Gene Aliases: 8030457G12Rik; hWNT5A; Wnt-5a; WNT5A
UniProt ID: (Human) P41221, (Mouse) P22725
Entrez Gene ID: (Human) 7474, (Rat) 64566, (Mouse) 22418
Molecular Function:
intercellular signal molecule
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