|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (Human) (C terminal).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Gel Shift (GS)||Assay-dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA1-20991 detects Wilm's tumor in Human, Mouse and Rat samples.
PA1-20991 has been successfully used in Immunohistochemistry (Paraffin) procedures. Predicted molecular weight of 51 kDa.
PA1-20991 immunogen corresponds to Synthetic peptide (Human) (C terminal).
Wilm's Tumor (WT), a sporadic and familial childhood kidney tumor, is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1, a zinc finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed infetal kidney and mesothelioma, and its expression has been suggested as a marker for Wilm's tumor and mesothelioma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Semiautomated quantitative image analysis of glomerular immunohistochemistry markers desmin, vimentin, podocin, synaptopodin and WT-1 in acute and chronic rat kidney disease models.
PA1-20991 was used in immunohistochemistry to assess immunohistochemistry markers using four different acute and chronic rat kidney disease models
|Funk J,Ott V,Herrmann A,Rapp W,Raab S,Riboulet W,Vandjour A,Hainaut E,Benardeau A,Singer T,Jacobsen B||Histochemistry and cell biology (145:315)||2016|