Invitrogen

XDH Recombinant Rabbit Monoclonal Antibody (ARC1385)

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XDH Antibody in Western Blot (WB) — Western Blot analysis of XDH performed on various cell lines using a XDH monoclonal antibody (Product # MA5-35747) at a dilution of 1:1,000. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000.

Product Details

MA5-35747

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-

Product Specifications
Species Reactivity	Human, Rat
Host/Isotype	Rabbit / IgG
Class	Recombinant Monoclonal
Type	Antibody
Clone	ARC1385
Immunogen	A synthesized peptide derived from human Xanthine Oxidase
Conjugate	Unconjugated
Form	Liquid
Concentration	0.55 mg/mL
Purification	Protein A
Storage buffer	PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2849647

Target Information

XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase; Xanthine oxidase; Xanthine oxidoreductase; XD; xdh antibody; xdha antibody; XO; XOR; xor antibody

Gene Aliases: XDH; XDHA; XO; XOR

UniProt ID: (Human) P47989, (Rat) P22985

Entrez Gene ID: (Human) 7498, (Rat) 497811

Molecular Function: oxidoreductase metabolite interconversion enzyme