Product References
XPF activates break-induced telomere synthesis.
Nature communications
Guh CY,Shen HJ,Chen LW,Chiu PC,Liao IH,Lo CC,Chen Y,Hsieh YH,Chang TC,Yen CP,Chen YY,Chen TW,Chen LY,Wu CS,Egly JM,Chu HC
MA5-12060 was used in Western Blotting to suggest that telomeric R-loops activate DDR via XPF to promote homologous recombination and telomere replication to drive ALT.
Sun Oct 02 00:00:00 EDT 2022
Impact of ERCC1, XPF and DNA Polymerase β Expression on Platinum Response in Patient-Derived Ovarian Cancer Xenografts.
Cancers
Guffanti F,Alvisi MF,Caiola E,Ricci F,De Maglie M,Soldati S,Ganzinelli M,Decio A,Giavazzi R,Rulli E,Damia G
Published figure using XPF monoclonal antibody (Product # MA5-12060) in Immunocytochemistry
Mon Aug 24 00:00:00 EDT 2020
Impact of ERCC1, XPF and DNA Polymerase β Expression on Platinum Response in Patient-Derived Ovarian Cancer Xenografts.
Cancers
Guffanti F,Alvisi MF,Caiola E,Ricci F,De Maglie M,Soldati S,Ganzinelli M,Decio A,Giavazzi R,Rulli E,Damia G
Published figure using XPF monoclonal antibody (Product # MA5-12060) in Immunocytochemistry
Mon Aug 24 00:00:00 EDT 2020
Impact of ERCC1, XPF and DNA Polymerase β Expression on Platinum Response in Patient-Derived Ovarian Cancer Xenografts.
Cancers
Guffanti F,Alvisi MF,Caiola E,Ricci F,De Maglie M,Soldati S,Ganzinelli M,Decio A,Giavazzi R,Rulli E,Damia G
Published figure using XPF monoclonal antibody (Product # MA5-12060) in Immunocytochemistry
Mon Aug 24 00:00:00 EDT 2020
Persistent 3'-phosphate termini and increased cytotoxicity of radiomimetic DNA double-strand breaks in cells lacking polynucleotide kinase/phosphatase despite presence of an alternative 3'-phosphatase.
DNA repair
Chalasani SL,Kawale AS,Akopiants K,Yu Y,Fanta M,Weinfeld M,Povirk LF
MA5-12060 was used in Western Blotting to suggest that, despite presence of an alternative 3'-phosphatase, loss of PNKP significantly sensitizes cells to 3'-phosphate-terminated DSBs, due to a 3'-dephosphorylation defect.
Wed Aug 01 00:00:00 EDT 2018
Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.
Genome biology
Galanos P,Pappas G,Polyzos A,Kotsinas A,Svolaki I,Giakoumakis NN,Glytsou C,Pateras IS,Swain U,Souliotis VL,Georgakilas AG,Geacintov N,Scorrano L,Lukas C,Lukas J,Livneh Z,Lygerou Z,Chowdhury D,Sørensen CS,Bartek J,Gorgoulis VG
Published figure using XPF monoclonal antibody (Product # MA5-12060) in Western Blot
Fri Mar 16 00:00:00 EDT 2018
A small molecule screen identifies an inhibitor of DNA repair inducing the degradation of TFIIH and the chemosensitization of tumor cells to platinum.
Chemistry & biology
Alekseev S,Ayadi M,Brino L,Egly JM,Larsen AK,Coin F
MA5-12060 was used in Western Blotting to find that spironolactone promotes a rapid and reversible degradation of XPB, a subunit of transcription/repair factor TFIIH.
Thu Mar 20 00:00:00 EDT 2014
Xeroderma pigmentosum group F protein binds to Eg5 and is required for proper mitosis: implications for XP-F and XFE.
Genes to cells : devoted to molecular & cellular mechanisms
Tan LJ,Saijo M,Kuraoka I,Narita T,Takahata C,Iwai S,Tanaka K
MA5-12060 was used in western blot to study the association between Eg5 and Xeroderma pigmentosum group F protein and the significance for mitosis and the pathogenesis of XP-F and XFE
Thu Mar 01 00:00:00 EST 2012
Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity.
Cellular and molecular life sciences : CMLS
Tomicic MT,Reischmann P,Rasenberger B,Meise R,Kaina B,Christmann M
MA5-12060 was used in western blot to study the role of delayed c-Fos activation in the adaptive response to UVC-induced DNA damage and cytotoxicity
Sun May 01 00:00:00 EDT 2011
Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells.
The Journal of biological chemistry
Muniandy PA,Thapa D,Thazhathveetil AK,Liu ST,Seidman MM
MA5-12060 was used in immunocytochemistry to study the repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells
Fri Oct 09 00:00:00 EDT 2009
Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.
The EMBO journal
Mocquet V,Lainé JP,Riedl T,Yajin Z,Lee MY,Egly JM
MA5-12060 was used in blocking or activating experiment to study the recruitment of repair factors during nucleotide excision repair and the initiating role played by XPG
Wed Jan 09 00:00:00 EST 2008
gamma-H2AX formation in response to interstrand crosslinks requires XPF in human cells.
DNA repair
Mogi S,Oh DH
MA5-12060 was used in western blot to examine the role of XPF
Sat Jun 10 00:00:00 EDT 2006
Phosphorylation of XPB helicase regulates TFIIH nucleotide excision repair activity.
The EMBO journal
Coin F,Auriol J,Tapias A,Clivio P,Vermeulen W,Egly JM
MA5-12060 was used in western blot to study the role of XPB helicase phosphorylation in the regulation of the nucleotide excision repair activity of TFIIH
Wed Dec 08 00:00:00 EST 2004