|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||GST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254|
|Storage buffer||TBS, pH 7.4|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12624 targets ZAP-70 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-12624 immunogen is gST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254.
Mutations in ZAP-70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP-70 expression also defines a subset of Chronic Lymphocytic Leukaemia (CLL) in patients with unmutated Ig gene and poor clinical course.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.