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|Tested species reactivity||Mouse , Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||GST-fusion protein of Human ZAP70, amino acids 282-307|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Our Pacific Blue™ dye is optimally excited by the violet laser and conjugates of this dye are strongly fluorescent even at neutral pH. Pacific Blue™ and Pacific Orange™ dye conjugates can be simultaneously excited at 405 nm and emit at 455 nm and 551 nm, respectively, facilitating two-color analysis.
Mutations in ZAP-70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP-70 expression also defines a subset of Chronic Lymphocytic Leukaemia (CLL) in patients with unmutated Ig gene and poor clinical course.
Analyte Specific Reagent
70 kDa zeta-associated protein, 70 kDa zeta-chain associated protein, syk-related tyrosine kinase, zeta chain of T cell receptor associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, 70kD, SRK, STD, TZK, ZAP-70, tyrosine-protein kinase ZAP-70, zeta-chain associated protein kinase, 70kD
ZAP-70, STD, STCD, TZK, IMD48, SRK, ADMIO2
Protein metabolism and modification Protein modification Protein phosphorylation Signal transduction Intracellular signaling cascade Immunity and defense Other immune and defense Developmental processes Embryogenesis Cell proliferation and differentiation