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Product Details
BS-13563R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ZBTB1/ZNF909, amino acids 151-250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain specific protein 2; Zinc finger and BTB domain-containing protein 1
Gene Aliases: 9430077A12; AI256369; Bsg2; C430003J21Rik; KIAA0997; ZBTB1; ZNF909
UniProt ID: (Human) Q9Y2K1, (Mouse) Q91VL9
Entrez Gene ID: (Human) 22890, (Mouse) 268564, (Rat) 314246
negative regulation of transcription from RNA polymerase II promoter
positive regulation of T cell mediated immunity
DNA repair
chromatin remodeling
cellular response to DNA damage stimulus
translesion synthesis
B cell differentiation
positive regulation of natural killer cell differentiation
T cell differentiation in thymus
cellular response to UV
mRNA transcription from RNA polymerase II promoter
innate immune response
positive regulation of T cell differentiation
thymus development
protein homooligomerization
positive regulation of pro-T cell differentiation
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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