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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human ZBTB16 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15667 targets ZBTB16 in IF and WB applications and shows reactivity with Human samples.
The MA5-15667 immunogen is purified recombinant fragment of human ZBTB16 expressed in E. Coli.
MA5-15667 detects ZBTB16 which has a predicted molecular weight of approximately 74kDa.
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia . Alternate transcriptional splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
PLZF; promyelocytic leukaemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); Zinc finger protein PLZF; ZNF145
PLZF; ZBTB16; ZNF145