|Tested species reactivity||Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human ZC11A|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ZC3H11A (zinc finger CCCH domain-containing protein 11A), also known as KIAA0663 or ZC3HDC11A, is an 810 amino acid protein that contains 3 C3 H1-type zinc fingers. ZC3H11A is expressed in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, fetal brain and fetal liver. The gene encoding ZC3H11A maps to human chromosome 1q32.1 and mouse chromosome 1 E4. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene on chromosome 1 which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.