Immunogen sequence: YGVLCIQEYR KNSKVESSTR NNFMGLKDHL GHDLGHLYVE STDPQLSPAV PWSTVENPSM DTVNVGKDEK EASEENASSG DSEENTN
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.
ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS), suggesting it also may play a role in host immunity and inflammatory response.
Protein Aliases: MCP induced protein 3; MCP-induced protein 3; Probable ribonuclease ZC3H12C; Zinc finger CCCH domain-containing protein 12C
Gene Aliases: KIAA1726; MCPIP3; ZC3H12C
UniProt ID: (Human) Q9C0D7
Entrez Gene ID: (Human) 85463
Molecular Function: endoribonuclease