|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 401 and 721 of Human ZC3HAV1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA5-31650 targets ZC3HAV1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31650 immunogen is recombinant fragment corresponding to a region within amino acids 401 and 721 of Human ZC3HAV1.
This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers.
PA5-31650 was used in western blot to study ZAP-defective human cancers and a characterization of alphavirus M1 as a selective oncolytic virus
|Lin Y,Zhang H,Liang J,Li K,Zhu W,Fu L,Wang F,Zheng X,Shi H,Wu S,Xiao X,Chen L,Tang L,Yan M,Yang X,Tan Y,Qiu P,Huang Y,Yin W,Su X,Hu H,Hu J,Yan G||Proceedings of the National Academy of Sciences of the United States of America (111:E4504)||2014|