|Immunohistochemistry (Paraffin) (IHC (P))||15 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from internal region of human SLC39A14.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Panda, Dog, Bat, Horse, Pig (100%) Orangutan, Gibbon, Monkey, Marmoset, Mouse, Hamster, Bovine (94%).
The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cig19; Irt-like protein 14; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; SLC39A14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt-; Zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14
Gene Aliases: cig19; HMNDYT2; KIAA0062; LZT-Hs4; NET34; SLC39A14; ZIP14
UniProt ID: (Human) Q15043
Entrez Gene ID: (Human) 23516
Molecular Function: transporter
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