OriGene

ZNF217 Monoclonal Antibody (OTI3G5), TrueMAB™

Product Image Gallery

ZNF217 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZNF217 (RC224371, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ZNF21. Positive lysates LY416585 (100 µg) and LC416585 (20 µg) can be purchased separately from OriGene.

ZNF217 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-ZNF217 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809028)(1:150).

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2000

Immunohistochemistry (Paraffin) (IHC (P))

1:150

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI3G5

Immunogen

Human recombinant protein fragment corresponding to amino acids 730-1048 of human ZNF217 produced in E.coli.

Conjugate

Unconjugated

Form

liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Target Information

Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Zinc finger protein 217

Gene Aliases: ZABC1; ZNF217

UniProt ID: (Human) O75362

Entrez Gene ID: (Human) 7764

Molecular Function: nucleic acid binding transcription factor zinc finger transcription factor

Function(s)

negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated regulation of transcription, DNA-templated signal transduction neurogenesis negative regulation of transcription, DNA-templated

Process(es)

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding transcription regulatory region DNA binding metal ion binding

ZNF217 Monoclonal Antibody (OTI3G5), TrueMAB™

Product Details

Target Information

References (0)

Bioinformatics

Material safety data sheets (MSDS)

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