Peptide Sequence: QKIDNPESQA NSGALDTNQV LLHKIPPRKR LRKRDSQVKS MKHNSRVKIH QKSCERQKAK EGNGCRKTFS RSTKQITFIR IHKGSQVCRC SECGKIFRNP RYFSVHKKIH T
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.
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Protein Aliases: DKFZp686K08243; HFB101; KRAB zinc finger protein HFB101; Neurotrophin receptor-interacting factor homolog; ZF2; Zinc finger protein 274; Zinc finger protein HFB101; Zinc finger protein with KRAB and SCAN domains 19; Zinc finger protein zfp2; ZKSCAN19
Gene Aliases: HFB101; SP2114; ZF2; ZKSCAN19; ZNF274; ZSCAN51
UniProt ID: (Human) Q96GC6
Entrez Gene ID: (Human) 10782
Molecular Function: nucleic acid binding