Peptide Sequence: CGKAFRRSSH LLRHQRIHTG DKNVQEPEQG EAWKSRMESQ LENVETPMSY KCNECERSFT QNTGLIEHQK IHTGEKPYQC NACGKGFTRI SYLVQHQRSH VGKNIL
ZNF306 is a protein coding gene. Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
Protein Aliases: Zf47; Zinc finger and SCAN domain-containing protein 13; Zinc finger protein 306; Zinc finger protein 309; Zinc finger protein 47 homolog; Zinc finger protein with KRAB and SCAN domains 3; zinc finger protein zfp47
Gene Aliases: dJ874C20.1; dJ874C20.1.; ZF47; zfp-47; ZFP306; ZFP47; ZKSCAN3; ZNF306; ZNF309; ZSCAN13; ZSCAN35
UniProt ID: (Human) Q9BRR0
Entrez Gene ID: (Human) 80317
Molecular Function: nucleic acid binding