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This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants.
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Protein Aliases: DNA-directed RNA polymerase I subunit H; DNA-directed RNA polymerase I subunit RPA12; nuclear RNA polymerase I small specific subunit; nuclear RNA polymerase I small specific subunit Rpa12 like; RNA polymerase I small specific subunit Rpa12; transcription-associated zinc ribbon protein; Zinc ribbon domain-containing protein 1
Gene Aliases: 1110014N07Rik; HTEX-6; HTEX6; hZR14; POLR1H; RPA12; tctex-6; TCTEX6; TEX6; ZNRD1; ZR14
UniProt ID: (Human) Q9P1U0, (Rat) Q6MFY5, (Mouse) Q791N7
Entrez Gene ID: (Human) 30834, (Rat) 361784, (Mouse) 66136
Molecular Function:
DNA-directed RNA polymerase
RNA metabolism protein
nucleic acid metabolism protein
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