Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.
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Protein Aliases: C9DUPq21.11; DFNA51; DUP9q21.11; Friedreich ataxia region gene X104 (tight junction protein ZO-2); Tight junction protein 2; tight junction protein 2 (zona occludens 2); Tight junction protein ZO-2; X104; ZO2; zona occludens 2; Zona occludens protein 2; Zonula occludens protein 2
Gene Aliases: C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; TJP2; X104; ZO-2; ZO2