Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DLK; Dual leucine zipper bearing kinase; dual leucine zipper kinase DLK; leucine zipper protein kinase; Leucine-zipper protein kinase; M3KC; MAP3K12; MAPK-upstream kinase; mitogen activated protein kinase kinase kinase 12; Mitogen-activated protein kinase kinase kinase 12; Mixed lineage kinase; MUK; protein kinase MUK; zipper (leucine) protein kinase; ZPK
DLK; MAP3K12; MEKK12; MUK; ZPK; ZPKP1