MA1-13003 detects ZPR1 in human and mouse samples.
MA1-13003 has been successfully been used in Immunofluorescence and Western Blot applications, where a band of ~50 kDa is detected.
The immunogen used to produce MA1-13003 was mouse ZPR1 protein.
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
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Protein Aliases: Zinc finger protein 259; Zinc finger protein ZPR1
Gene Aliases: AI303781; Zfp259; ZNF259; ZPR1