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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 277 of ZWINT|
|Storage buffer||PBS, pH 7|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17284 targets ZWINT in WB applications and shows reactivity with Human samples.
The MA5-17284 immunogen is recombinant fragment contains a sequence corresponding to a region within amino acids 1 and 277 of ZWINT.
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
human ZW10 interacting protein-1; HZwint-1; KNTC2AP; SNAP25 interacting protein of 30 kDa; ZW10 interactor, kinetochore protein; zwint-1; ZWINT1
HZwint-1; KNTC2AP; SIP30; ZWINT; ZWINT1