This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: human ZW10 interacting protein-1; SNAP25 interacting protein of 30 kDa; ZW10 interactor; ZW10 interactor, kinetochore protein; ZW10-interacting protein 1; Zwint-1
Gene Aliases: 2010007E07Rik; 2600001N01Rik; D10Ertd749e; HZwint-1; KNTC2AP; SIP30; ZWINT; Zwint-1; ZWINT1