|Western Blot (WB)||Assay dependent|
|Gel Shift (GS)||See 1 publications below|
|Tested Species reactivity||Chicken|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Full length native alpha actinin purified from chicken gizzard.|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-28036 detects alpha Actinin from chicken samples. Expected to cross-react with a wide range of tther species due to sequence homology.
PA1-28036 has been successfully used in immunofluorescence and Western blot applications.
The PA1-28036 immunogen is full length native alpha actinin purified from chicken gizzard.
Alpha Actinin is an actin binding protein present in both muscle and non-muscle cells. It has a molecular weight of 100,000 daltons and forms dimers in solution. In normal skeletal muscle alpha actinin is associated with the z-discs that define muscle sarcomeres. In smooth muscle alpha actinin has been detected in dense bodies and plaques characteristic of the tissue. Immunofluorescent labeling of a large variety of cells using antibody to alpha actinin reveals extensive association of the proteins with actin containing stress fibers and in particular with their membrane bound termini.
Protein Aliases: ACTN1; Alpha-actinin cytoskeletal isoform; Alpha-actinin-1; F-actin cross-linking protein; Non-muscle alpha-actinin-1; RCJMB04_23c5
Gene Aliases: ACTN1; RCJMB04_23c5
UniProt ID: (Chicken) P05094
Entrez Gene ID: (Chicken) 373918