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|Tested species reactivity||Chicken|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Full length native alpha actinin purified from chicken gizzard.|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Gel Shift (GS)||See 1 publications below|
PA1-28036 detects alpha Actinin from chicken samples. Expected to cross-react with a wide range of tther species due to sequence homology.
PA1-28036 has been successfully used in immunofluorescence and Western blot applications.
The PA1-28036 immunogen is full length native alpha actinin purified from chicken gizzard.
Alpha Actinin is an actin binding protein present in both muscle and non-muscle cells. It has a molecular weight of 100,000 daltons and forms dimers in solution. In normal skeletal muscle alpha actinin is associated with the z-discs that define muscle sarcomeres. In smooth muscle alpha actinin has been detected in dense bodies and plaques characteristic of the tissue. Immunofluorescent labeling of a large variety of cells using antibody to alpha actinin reveals extensive association of the proteins with actin containing stress fibers and in particular with their membrane bound termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
α -Actinin TvACTN3 of Trichomonas vaginalis is an RNA-binding protein that could participate in its posttranscriptional iron regulatory mechanism.
PA1-28036 was used in EMSA to study the potential role of the Trichomonas vaginalis protein TvACTN3 in an iron-regulated transcription system
|Calla-Choque JS,Figueroa-Angulo EE,Ávila-González L,Arroyo R||BioMed research international (2014:null)||2014|
ACTN1; alpha-actinin cytoskeletal isoform; alpha-actinin-1; F-actin cross-linking protein; non-muscle alpha-actinin-1; RCJMB04_23c5