|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids C-terminus of human Catenin-alpha2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 100 kDa.
Purity is >95% by SDS-PAGE.
a-catenins are a group of proteins associated with cadherin cell-cell adhesion molecules and play indispensable roles in the function of the cadherins. a N-catenin is a linker between cadherin adhesion receptors and the Actin cytoskeleton and is essential for stabilizing dendritic spines in rodent hippocampal neurons in culture. A deletion in this protein causes cerebellar and hippocampal lamination defects and impaired startle reaction. a E- and a N-catenin appear to co-localize in cell bodies of neurons in dorsal root ganglia. In mice, a N-catenin was found to occur at the roof plate of the mesencephalon and diencephalon, coinciding with Wnt-1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 102 kDa cadherin-associated protein; alpha E catenin; Alpha E-catenin; Alpha N-catenin; alpha(E)-catenin; alpha(N)-catenin; Alpha-catenin-related protein; alpha-E-catenin; alpha-N-catenin; alphaE-catenin; alphaN-catenin; cadherin associated protein; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; CAP102; CAPR; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; catenin alpha 1; catenin alpha 2; Catenin alpha-1; Catenin alpha-2; Catenin alpha1; Catenin alpha2; catenin, alpha 1; Catenin-alpha1; Catenin-alpha2; cerebellar deficient folia; CTNNA1; CTNNA2; Renal carcinoma antigen NY-REN-13
Gene Aliases: 2010010M04Rik; AA517462; AI481747; AI988031; CAP-R; CAP102; CAPR; Catna; Catna1; Catna2; cdf; chp; CT114; CTNNA1; CTNNA2; CTNR; MDPT2
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