Product References
Inhibition of Ubiquitin-Specific Protease-13 Improves Behavioral Performance in Alpha-Synuclein Expressing Mice.
International journal of molecular sciences
Liu X,Balaraman K,Lynch CC,Hebron M,Shah PK,Hu S,Stevenson M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Western Blot
Sat Jul 23 00:00:00 EDT 2022
Inhibition of Ubiquitin-Specific Protease-13 Improves Behavioral Performance in Alpha-Synuclein Expressing Mice.
International journal of molecular sciences
Liu X,Balaraman K,Lynch CC,Hebron M,Shah PK,Hu S,Stevenson M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Western Blot
Sat Jul 23 00:00:00 EDT 2022
Vocal changes in a zebra finch model of Parkinson's disease characterized by alpha-synuclein overexpression in the song-dedicated anterior forebrain pathway.
PloS one
Medina CA,Vargas E,Munger SJ,Miller JE
AHB0261 was used in Immunohistochemistry to determine if viral-mediated expression of human wild-type αsyn in the adult song system changes song output.
Fri May 06 00:00:00 EDT 2022
α-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson's disease.
Free radical biology & medicine
A A,W C,N N,L M,M D,Zhang DD
AHB0261 was used in Western Blotting to indicate that NRF2 is a critical anti-ferroptotic mediator of neuronal survival, and that the vicious cycle of α-syn overexpression and NRF2 suppression, leading to enhanced neuronal ferroptotic cell death, could represent a targetable and currently untapped means of preventing PD onset and progression.
Tue Nov 01 00:00:00 EDT 2022
Alteration of EIF2 Signaling, Glycolysis, and Dopamine Secretion in Form-Deprived Myopia in Response to 1% Atropine Treatment: Evidence From Interactive iTRAQ-MS and SWATH-MS Proteomics Using a Guinea Pig Model.
Frontiers in pharmacology
Zhu Y,Bian JF,Lu DQ,To CH,Lam CS,Li KK,Yu FJ,Gong BT,Wang Q,Ji XW,Zhang HM,Nian H,Lam TC,Wei RH
AHB0261 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal that retinal EIF2 signaling, glycolysis, and dopamine secretion through SNCA are implicated in atropine treatment of myopia in the FDM-induced guinea pig model.
Wed Feb 16 00:00:00 EST 2022
Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease.
Frontiers in cell and developmental biology
Cai M,Chai S,Xiong T,Wei J,Mao W,Zhu Y,Li X,Wei W,Dai X,Yang B,Liu W,Shu B,Wang M,Lu T,Cai Y,Zheng Z,Mei Z,Zhou Y,Yang J,Zhao J,Shen L,Ho JWK,Chen J,Xiong N
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Western Blot
Fri Sep 10 00:00:00 EDT 2021
Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.
Metabolites
Liu X,Balaraman K,Lynch CC,Hebron M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.
Metabolites
Liu X,Balaraman K,Lynch CC,Hebron M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.
Metabolites
Liu X,Balaraman K,Lynch CC,Hebron M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.
Metabolites
Liu X,Balaraman K,Lynch CC,Hebron M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.
Metabolites
Liu X,Balaraman K,Lynch CC,Hebron M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.
Metabolites
Liu X,Balaraman K,Lynch CC,Hebron M,Wolf C,Moussa C
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
Proceedings of the National Academy of Sciences of the United States of America
Brekk OR,Honey JR,Lee S,Hallett PJ,Isacson O
AHB0261 was used in Immunohistochemistry to determine human PD SN neutral lipid content and distribution in dopaminergic neurons, astrocytes, and microglia relative to age-matched healthy subject controls.
Tue Nov 03 00:00:00 EST 2020
Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
Proceedings of the National Academy of Sciences of the United States of America
Brekk OR,Honey JR,Lee S,Hallett PJ,Isacson O
AHB0261 was used in Immunohistochemistry to determine human PD SN neutral lipid content and distribution in dopaminergic neurons, astrocytes, and microglia relative to age-matched healthy subject controls.
Tue Nov 03 00:00:00 EST 2020
Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
Proceedings of the National Academy of Sciences of the United States of America
Brekk OR,Honey JR,Lee S,Hallett PJ,Isacson O
AHB0261 was used in Immunohistochemistry to determine human PD SN neutral lipid content and distribution in dopaminergic neurons, astrocytes, and microglia relative to age-matched healthy subject controls.
Tue Nov 03 00:00:00 EST 2020
Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations.
eLife
Cupo RR,Shorter J
AHB0261 was used in Western Blotting to investigate whether Skd3 (encoded by human CLPB) might act as a mitochondrial protein disaggregase in metazoa.
Tue Jun 23 00:00:00 EDT 2020
A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology.
International journal of stroke : official journal of the International Stroke Society
Humphreys CA,Jansen MA,Muñoz Maniega S,González-Castro V,Pernet C,Deary IJ,Al-Shahi Salman R,Wardlaw JM,Smith C
AHB0261 was used in Immunohistochemistry to identify and define the cellular characteristics of small vessel disease lesions in human post-mortem brain tissue, in relation to the lesions seen on neuroimaging.
Mon Apr 01 00:00:00 EDT 2019
Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein.
Acta neuropathologica communications
Krejciova Z,Carlson GA,Giles K,Prusiner SB
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunocytochemistry
Mon May 20 00:00:00 EDT 2019
Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease.
Scientific reports
Uehara T,Choong CJ,Nakamori M,Hayakawa H,Nishiyama K,Kasahara Y,Baba K,Nagata T,Yokota T,Tsuda H,Obika S,Mochizuki H
AHB0261 was used in Immunohistochemistry-immunofluorescence to suggest that AmNA-ASO is a promising therapeutic strategy for SNCA-associated pathology in PD.
Tue May 21 00:00:00 EDT 2019
Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice.
EBioMedicine
Cai W,Feng D,Schwarzschild MA,McLean PJ,Chen X
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Thu Mar 01 00:00:00 EST 2018
Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice.
EBioMedicine
Cai W,Feng D,Schwarzschild MA,McLean PJ,Chen X
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Thu Mar 01 00:00:00 EST 2018
A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia.
Acta neuropathologica communications
Henrich MT,Geibl FF,Lee B,Chiu WH,Koprich JB,Brotchie JM,Timmermann L,Decher N,Matschke LA,Oertel WH
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunofluorescence
Thu May 10 00:00:00 EDT 2018
DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy.
Frontiers in aging neuroscience
Xu CY,Kang WY,Chen YM,Jiang TF,Zhang J,Zhang LN,Ding JQ,Liu J,Chen SD
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Western Blot
Thu Oct 01 00:00:00 EDT 2020
Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression.
Scientific reports
Fischer DL,Manfredsson FP,Kemp CJ,Cole-Strauss A,Lipton JW,Duffy MF,Polinski NK,Steece-Collier K,Collier TJ,Gombash SE,Buhlinger DJ,Sortwell CE
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunohistochemistry
Mon Nov 27 00:00:00 EST 2017
Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society
Caviness JN,Lue LF,Hentz JG,Schmitz CT,Adler CH,Shill HA,Sabbagh MN,Beach TG,Walker DG
AHB0261 was used in western blot to analyze the correlation between brain wave spectra in Parkinson's disease and cortical phosphorylated alpha-synuclein levels
Fri Jul 01 00:00:00 EDT 2016
Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core.
Scientific reports
de Oliveira GA,Marques MA,Cruzeiro-Silva C,Cordeiro Y,Schuabb C,Moraes AH,Winter R,Oschkinat H,Foguel D,Freitas MS,Silva JL
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Dot blot
Wed Nov 30 00:00:00 EST 2016
Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core.
Scientific reports
de Oliveira GA,Marques MA,Cruzeiro-Silva C,Cordeiro Y,Schuabb C,Moraes AH,Winter R,Oschkinat H,Foguel D,Freitas MS,Silva JL
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Dot blot
Wed Nov 30 00:00:00 EST 2016
Salivary total α-synuclein, oligomeric α-synuclein and SNCA variants in Parkinson's disease patients.
Scientific reports
Kang W,Chen W,Yang Q,Zhang L,Zhang L,Wang X,Dong F,Zhao Y,Chen S,Quinn TJ,Zhang J,Chen S,Liu J
AHB0261 was used in western blot to identify oligomeric alpha-synuclein, total alpha-synuclein, and SNCA variants in Parkinson's disease patients
Thu Jun 23 00:00:00 EDT 2016
A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy.
Molecular neurodegeneration
Spencer B,Valera E,Rockenstein E,Trejo-Morales M,Adame A,Masliah E
AHB0261 was used in western blot to reduce alpha-synuclein accumulation in a mouse model of multiple system atrophy by using a brain-targeted, modified neurosin (kallikrein-6)
Wed Sep 23 00:00:00 EDT 2015
Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease.
Journal of neuroinflammation
Kim C,Ojo-Amaize E,Spencer B,Rockenstein E,Mante M,Desplats P,Wrasidlo W,Adame A,Nchekwube E,Oyemade O,Okogun J,Chan M,Cottam H,Masliah E
AHB0261 was used in immunohistochemistry to study a mouse model of Parkinson's disease for hypoestoxide to reduce neuroinflammation and alpha-synuclein accumulation
Fri Dec 18 00:00:00 EST 2015
Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.
Acta neuropathologica communications
Bourdenx M,Dovero S,Engeln M,Bido S,Bastide MF,Dutheil N,Vollenweider I,Baud L,Piron C,Grouthier V,Boraud T,Porras G,Li Q,Baekelandt V,Scheller D,Michel A,Fernagut PO,Georges F,Courtine G,Bezard E,Dehay B
AHB0261 was used in immunohistochemistry to study alpha-synuclein overexpression by lack of an additive role of aging in nigrostriatal neurodegeneration
Sat Jul 25 00:00:00 EDT 2015
Using gastrocnemius sEMG and plasma α-synuclein for the prediction of freezing of gait in Parkinson's disease patients.
PloS one
Wang XY,Kang WY,Yang Q,Zhang LY,Chen SD,Liu J
AHB0261 was used in ELISA to investigate the use of surface electromyograph and plasma α-synuclein levels as predictors of the freezing of gait seen in patients with Parkinson's disease.
Wed Oct 29 00:00:00 EDT 2014
Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system.
PloS one
Gombash SE,Manfredsson FP,Kemp CJ,Kuhn NC,Fleming SM,Egan AE,Grant LM,Ciucci MR,MacKeigan JP,Sortwell CE
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunofluorescence
Wed Dec 17 00:00:00 EST 2014
Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system.
PloS one
Gombash SE,Manfredsson FP,Kemp CJ,Kuhn NC,Fleming SM,Egan AE,Grant LM,Ciucci MR,MacKeigan JP,Sortwell CE
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunofluorescence
Wed Dec 17 00:00:00 EST 2014
Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system.
PloS one
Gombash SE,Manfredsson FP,Kemp CJ,Kuhn NC,Fleming SM,Egan AE,Grant LM,Ciucci MR,MacKeigan JP,Sortwell CE
Published figure using alpha Synuclein monoclonal antibody (Product # AHB0261) in Immunofluorescence
Wed Dec 17 00:00:00 EST 2014
Neuropathology in mice expressing mouse alpha-synuclein.
PloS one
Rieker C,Dev KK,Lehnhoff K,Barbieri S,Ksiazek I,Kauffmann S,Danner S,Schell H,Boden C,Ruegg MA,Kahle PJ,van der Putten H,Shimshek DR
AHB0261 was used in western blot to characterize mice that over express murine alpha-Synuclein
Thu Mar 01 00:00:00 EST 2012