|Tested species reactivity||Many|
|Published species reactivity||Bovine, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Fraction of tubulin purified from porcine brain by two cycles of polymerization - depolymerization.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 3 publications below|
This antibody recognizes the defined epitope (aa 65-97) on N-terminal structural domain of alpha-tubulin.
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Sera from early-onset, severely preeclamptic women directly modulate HLA-E expression in the EA.hy296 endothelial cell line.
MA1-19581 was used in western blot to study the modulation of endothelial cell line expression of HLA-E by sera obtained from women with severe early onset preeclampsia
|Bueno-Sánchez JC,Peña-Alzate S,Peña RB,Agudelo-Jaramillo B,Cadavid-Jaramillo AP,Chaouat G,Maldonado-Estrada JG||Journal of reproductive immunology (104-105:68)||2014|
Proteinase-activated receptor 2 expression in the intestinal tract of the horse.
MA1-19581 was used in western blot to study the equine intestinal expression of PAR2
|Zannoni A,Bombardi C,Dondi F,Morini M,Forni M,Chiocchetti R,Spadari A,Romagnoli N||Research in veterinary science (96:464)||2014|
Methoxychlor and triclosan stimulates ovarian cancer growth by regulating cell cycle- and apoptosis-related genes via an estrogen receptor-dependent pathway.
MA1-19581 was used in western blot to study the role of ER-dependent modulation of cell cycle and apoptosis genes in the mechanism by which methoxychlor and triclosan promote the growth of ovarian cancer
|Kim JY,Yi BR,Go RE,Hwang KA,Nam KH,Choi KC||Environmental toxicology and pharmacology (37:1264)||2014|