Product References
Using ZINC08918027 inhibitor to determine Aurora kinase-chromosomal passenger complex isoforms in mouse oocytes.
BMC research notes
Kratka C,Drutovic D,Blengini CS,Schindler K
322588 was used in Immunohistochemistry to examine the utility of ZINC08918027, an inhibitor that prevents the interaction between AURKB and INCENP in mitotic cells, in disrupting chromosomal passenger complex function in mouse oocytes.
Mon Mar 07 00:00:00 EST 2022
Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle.
The Journal of general physiology
Coleman AK,Joca HC,Shi G,Lederer WJ,Ward CW
322588 was used in Western Blot to add to growing evidence that microtubules contribute to the mechanobiology of striated muscle in health and disease.
Mon Jul 05 00:00:00 EDT 2021
Aurora kinase A is essential for meiosis in mouse oocytes.
PLoS genetics
Blengini CS,Ibrahimian P,Vaskovicova M,Drutovic D,Solc P,Schindler K
322588 was used in Immunocytochemistry to conclude that AURKA has multiple functions essential to completing MI that are distinct from AURKB and AURKC.
Thu Apr 01 00:00:00 EDT 2021
The effects of antiviral treatment on breast cancer cell line.
Infectious agents and cancer
Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2020
The effects of antiviral treatment on breast cancer cell line.
Infectious agents and cancer
Shaimerdenova M,Karapina O,Mektepbayeva D,Alibek K,Akilbekova D
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2020
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†.
Biology of reproduction
Devlin DJ,Nozawa K,Ikawa M,Matzuk MM
322588 was used in Immunocytochemistry-immunoflourescence to study the role of family with sequence similarity 170 (FAM170) members A and B in male mice fertility.
Tue Aug 04 00:00:00 EDT 2020
Knockout of mouse receptor accessory protein 6 leads to sperm function and morphology defects†.
Biology of reproduction
Devlin DJ,Agrawal Zaneveld S,Nozawa K,Han X,Moye AR,Liang Q,Harnish JM,Matzuk MM,Chen R
322588 was used in Immunohistochemistry to reveal an important role for REEP6 in sperm motility and morphology and is the first reported function for a REEP protein in reproductive processes.
Tue May 26 00:00:00 EDT 2020
NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.
Cell reports
Nourreddine S,Lavoie G,Paradis J,Ben El Kadhi K,Méant A,Aubert L,Grondin B,Gendron P,Chabot B,Bouvier M,Carreno S,Roux PP
322588 was used in Immunocytochemistry-immunoflourescence to indicate that the NF45-NF90 complex plays essential roles in mitosis by competing with the SMD machinery for a common set of mRNAs.
Tue May 19 00:00:00 EDT 2020
The cyclin B2/CDK1 complex inhibits separase activity in mouse oocyte meiosis I.
Development (Cambridge, England)
Li J,Ouyang YC,Zhang CH,Qian WP,Sun QY
322588 was used in Immunocytochemistry-Immunofluorescence to study the interaction between cyclin B2/CDK1 and separase in mouse oocytes.
Mon Dec 02 00:00:00 EST 2019
Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice.
Development (Cambridge, England)
Rodriguez A,Briley SM,Patton BK,Tripurani SK,Rajapakshe K,Coarfa C,Rajkovic A,Andrieux A,Dejean A,Pangas SA
322588 was used in Immunocytochemistry-immunoflourescence to show that SUMOylation is required in the mammalian oocyte during folliculogenesis for both oocyte development and communication with ovarian somatic cells.
Mon Dec 02 00:00:00 EST 2019
A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma.
Cancers
White CL,Jayasekara WSN,Picard D,Chen J,Watkins DN,Cain JE,Remke M,Gough DJ
322588 was used in Immunohistochemistry to identify a sex-specific role for the transcription factor Signal Transducer and Activator of Transcription 3 in the Sonic Hedgehog medulloblastoma subgroup.
Fri Nov 01 00:00:00 EDT 2019
Cigarette and ENDS preparations differentially regulate ion channels and mucociliary clearance in primary normal human bronchial 3D cultures.
American journal of physiology. Lung cellular and molecular physiology
Rayner RE,Makena P,Prasad GL,Cormet-Boyaka E
322588 was used in Immunohistochemistry to compare the effects of acute exposure of primary normal human bronchial epithelial (NHBE) 3D cultures at air-liquid interface to combustible cigarette and ENDS preparations on mucociliary function, including ion channel function, ciliary beat frequency (CBF), and airway surface liquid (ASL) height.
Thu Aug 01 00:00:00 EDT 2019
A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis.
Nature communications
Kim YH,Choi J,Yang MJ,Hong SP,Lee CK,Kubota Y,Lim DS,Koh GY
322588 was used in Immunocytochemistry-Immunofluorescence to delineate a crucial coupling between extracellular hypoxia and an intracellular reactive oxygen species-MST1-FOXO1 cascade in establishing endothelial tip cell polarity during sprouting angiogenesis.
Tue Feb 19 00:00:00 EST 2019
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
Molecular cell
Liccardi G,Ramos Garcia L,Tenev T,Annibaldi A,Legrand AJ,Robertson D,Feltham R,Anderton H,Darding M,Peltzer N,Dannappel M,Schünke H,Fava LL,Haschka MD,Glatter T,Nesvizhskii A,Schmidt A,Harris PA,Bertin J,Gough PJ,Villunger A,Silke J,Pasparakis M,Bianchi K,Meier P
322588 was used in Immunocytochemistry-immunoflourescence to assess the role of ripoptosome-mediated regulation of Polo-like kinase 1 in faithful chromosome segregation during mitosis.
Thu Feb 07 00:00:00 EST 2019
Optimization of Normal Human Bronchial Epithelial (NHBE) Cell 3D Cultures for in vitro Lung Model Studies.
Scientific reports
Rayner RE,Makena P,Prasad GL,Cormet-Boyaka E
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Thu Jan 24 00:00:00 EST 2019
LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.
PLoS pathogens
De Leo A,Deng Z,Vladimirova O,Chen HS,Dheekollu J,Calderon A,Myers KA,Hayden J,Keeney F,Kaufer BB,Yuan Y,Robertson E,Lieberman PM
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunocytochemistry
Tue Jan 01 00:00:00 EST 2019
Rainbow-Seq: Combining Cell Lineage Tracing with Single-Cell RNA Sequencing in Preimplantation Embryos.
iScience
Biase FH,Wu Q,Calandrelli R,Rivas-Astroza M,Zhou S,Chen Z,Zhong S
322588 was used in Immunocytochemistry to develop and present Rainbow-seq, a method that combines cell division lineage tracing with single-cell RNA sequencing in mouse embryos.
Fri Sep 28 00:00:00 EDT 2018
Automated classification and characterization of the mitotic spindle following knockdown of a mitosis-related protein.
BMC bioinformatics
Khushi M,Dean IM,Teber ET,Chircop M,Arthur JW,Flores-Rodriguez N
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Thu Dec 28 00:00:00 EST 2017
Monomethyl Auristatin E Phosphate Inhibits Human Prostate Cancer Growth.
The Prostate
Cunningham D,Parajuli KR,Zhang C,Wang G,Mei J,Zhang Q,Liu S,You Z
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Tue Nov 01 00:00:00 EDT 2016
Monomethyl Auristatin E Phosphate Inhibits Human Prostate Cancer Growth.
The Prostate
Cunningham D,Parajuli KR,Zhang C,Wang G,Mei J,Zhang Q,Liu S,You Z
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Tue Nov 01 00:00:00 EDT 2016
Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes.
Journal of cell science
Balboula AZ,Nguyen AL,Gentilello AS,Quartuccio SM,Drutovic D,Solc P,Schindler K
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Sat Oct 01 00:00:00 EDT 2016
The Clathrin-dependent Spindle Proteome.
Molecular & cellular proteomics : MCP
Rao SR,Flores-Rodriguez N,Page SL,Wong C,Robinson PJ,Chircop M
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunocytochemistry
Mon Aug 01 00:00:00 EDT 2016
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.
Nature communications
Stritt S,Nurden P,Favier R,Favier M,Ferioli S,Gotru SK,van Eeuwijk JM,Schulze H,Nurden AT,Lambert MP,Turro E,Burger-Stritt S,Matsushita M,Mittermeier L,Ballerini P,Zierler S,Laffan MA,Chubanov V,Gudermann T,Nieswandt B,Braun A
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Tue Mar 29 00:00:00 EDT 2016
Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture.
Nature communications
Stritt S,Nurden P,Favier R,Favier M,Ferioli S,Gotru SK,van Eeuwijk JM,Schulze H,Nurden AT,Lambert MP,Turro E,Burger-Stritt S,Matsushita M,Mittermeier L,Ballerini P,Zierler S,Laffan MA,Chubanov V,Gudermann T,Nieswandt B,Braun A
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Tue Mar 29 00:00:00 EDT 2016
Open-source image reconstruction of super-resolution structured illumination microscopy data in ImageJ.
Nature communications
Müller M,Mönkemöller V,Hennig S,Hübner W,Huser T
322588 was used in immunocytochemistry to determine characteristics of ImageJ through open-source image reconstruction of super-resolution structured illumination microscopy data
Mon Mar 21 00:00:00 EDT 2016
Knockdown of RBBP7 unveils a requirement of histone deacetylation for CPC function in mouse oocytes.
Cell cycle (Georgetown, Tex.)
Balboula AZ,Stein P,Schultz RM,Schindler K
322588 was used in Immunocytochemistry-immunoflourescence to identify RBBP7 as a novel regulator of histone deacetylation during oocyte maturation and provide evidence that such deacetylation is required for proper chromosome segregation.
Thu Apr 16 00:00:00 EDT 2015
RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse.
Biology of reproduction
Balboula AZ,Stein P,Schultz RM,Schindler K
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunofluorescence
Wed Apr 01 00:00:00 EDT 2015
Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury.
Cellular and molecular life sciences : CMLS
Pratt SJP,Shah SB,Ward CW,Kerr JP,Stains JP,Lovering RM
Published figure using alpha Tubulin monoclonal antibody (Product # 322588) in Immunohistochemistry
Thu Jan 01 00:00:00 EST 2015
Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes.
Journal of cell science
Nguyen AL,Gentilello AS,Balboula AZ,Shrivastava V,Ohring J,Schindler K
322588 was used in Immunofluorescence to implicate haspin as a regulator of the CPC and chromosome segregation during MI, while highlighting important differences in how chromosome segregation is regulated between MI and mitosis.
Mon Dec 01 00:00:00 EST 2014
Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.
Nature communications
Bender M,Stritt S,Nurden P,van Eeuwijk JM,Zieger B,Kentouche K,Schulze H,Morbach H,Stegner D,Heinze KG,Heinze K,Dütting S,Gupta S,Witke W,Falet H,Fischer A,Hartwig JH,Nieswandt B
322588 was used in Immunocytochemistry-immunofluorescence to identify Profilin1 as a regulator of microtubule organisation and identify the mechanism underlying the platelet formation defect in Wiskott-Aldrich syndrome.
Thu Sep 04 00:00:00 EDT 2014
Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes.
PLoS genetics
Balboula AZ,Schindler K
322588 was used in immunocytochemistry to determine how disruption of aurora C kinase reveals functions of aurora B kinase during meiosis in mouse oocytes
Sat Feb 01 00:00:00 EST 2014
CLP36 is a negative regulator of glycoprotein VI signaling in platelets.
Circulation research
Gupta S,Braun A,Morowski M,Premsler T,Bender M,Nagy Z,Sickmann A,Hermanns HM,Bösl M,Nieswandt B
322588 was used in Immunofluorescecne to examine the role of CLP36 in platelet physiology both in vitro and in vivo.
Fri Nov 09 00:00:00 EST 2012