Keep as concentrated solution.
Positive Control: 293T, A431, HeLa, HepG2, NIH-3T3, mouse brain, PC-12, rat brain, drosophila, zebrafish eye, Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, U87-MG.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha; alpha 1b antibody; alpha tubulin; alpha tubulin antibody; Alpha-tubulin 2; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin ubiquitous; alpha-tubulin ubiquitous antibody; Detyrosinated tubulin alpha-1B chain; K-ALPHA-1 antibody; TUBA1B antibody; tubulin; Tubulin alpha-1B chain; tubulin alpha-1B chain antibody; Tubulin alpha-2 chain; Tubulin alpha-ubiquitous chain; tubulin alpha-ubiquitous chain antibody; Tubulin K-alpha-1; tubulin K-alpha-1 antibody; tubulin, alpha 1; tubulin, alpha 1b; tubulin, alpha 2; tubulin, alpha, ubiquitous; ubiquitous antibody
Gene Aliases: cb944; fb22g06; K-ALPHA-1; RGD1565476; tuba1; TUBA1B; Tuba2; wu:fb22g06