The antibody target was verified by IP Mass Spectrometry to ensure the antibody binds to the antigen stated. View details.
|Gel Shift (GS)||Assay Dependent|
|Immunofluorescence (IF)||1:50 - 1:1000|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100 - 1:1000|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1:500 - 1:1000|
|Tested Species reactivity||Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Mouse|
|Immunogen||Recombinant beta Catenin protein.|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-301 detects beta Catenin from human, mouse, monkey, and rat samples.
MA1-301 has been successfully used in Western blot, gel shift, immunohistochemistry (paraffin), and immunofluorescence applications. By Western blot this antibody detects a ~94 kDa protein representing beta Catenin.
Beta Catenin is thought to play a role in cell-cell communication and adhesion, and possibly cell morphology. In the nucleus, beta Catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation. This influence on cell proliferation is the molecular basis for the role of beta Catenin in tumorgenesis, in particular solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-catenin; Cadherin associated protein, Catenin beta 1, CATNB, CTNNB, beta-catenin, beta catenin, CTNNB1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta; Catenin beta-1
Gene Aliases: armadillo; Bfc; Catnb; CTNNB; CTNNB1; Mesc; MRD19; OK/SW-cl.35; PRO2286
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.