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|Tested species reactivity||Tag|
|Published species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Synthetic peptide corresponding to residues M E Q K L I S E E D L G C of human c-Myc.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunofluorescence (IF)||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA3-981 detects c-Myc tagged proteins.
PA3-981 has been successfully used in immunofluorescence, immunoprecipitation, and Western blot procedures. By Western blot it detects a ~41 kDa protein representing c-Myc.
The PA3-981 immunogen is a synthetic peptide corresponding to residues M E Q K L I S E E D L G C of human c-Myc.
The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation. In addition, deregulated expression of c-Myc induces apoptosis in different cell types, with c-myc requiring p53 for apoptosis in many cell types. This fact indicates heterogeneous mechanisms for c-myc-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Functional and molecular evidence of MaxiK channel beta1 subunit decrease with coronary artery ageing in the rat.
PA3-981 was used in western blot to investigate the relationship between Maxi potassium channel expression and coronary artery ageing
|Nishimaru K,Eghbali M,Lu R,Marijic J,Stefani E,Toro L||The Journal of physiology (559:849)||2004|
avian myelocytomatosis viral oncogene homolog; c Myc; Cellular myelocytomatosis oncogene; class E basic helix-loop-helix protein 39; Myc proto oncogene protein; myc-related translation/localization regulatory factor; Myc2; Niard; Nird; proto-oncogene c-Myc; transcription factor p64; v myc avian myelocytomatosis viral oncogene hom; v-myc myelocytomatosis viral oncogene homolog
BHLHE39; c-Myc; MRTL; MYC; MYCC