|Flow Cytometry (Flow)||1:20|
|Immunoprecipitation (IP)||10 ul|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 2 publications below|
|ChIP assay (ChIP)||See 2 publications below|
|Tested Species reactivity||Chicken, Human, Mouse|
|Published species reactivity||Yeast , Cat|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||A synthetic peptide, corresponding to amino acid residues 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from the C terminus of c-myc,coupled to KLH.|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
c-Myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions. An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; c-Myc; c-myc proto-oncogene; Cellular myelocytomatosis oncogene; Class E basic helix-loop-helix protein 39; Myc proto oncogene protein; Myc proto-oncogene protein; myc-related translation/localization regulatory factor; Myc2; Niard; Nird; Proto-oncogene c-Myc; Transcription factor p64; v myc avian myelocytomatosis viral oncogene hom; v-myc myelocytomatosis viral oncogene homolog
Gene Aliases: AU016757; BHLHE39; c-Myc; MRTL; MYC; Myc2; MYCC; Niard; Nird
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