|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||A 32 amino acid synthetic peptide (aa 408-439) derived from the C-terminus of the human c-myc protein.|
|Storage buffer||PBS, pH 7.4, with 1% BSA, 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
c-Myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions. An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Proton-sensing G-protein-coupled receptors.
13-2511 was used in immunohistochemistry (paraffin) to examine the role of OGR1 and GPR4 in pH homeostasis.
|Ludwig MG,Vanek M,Guerini D,Gasser JA,Jones CE,Junker U,Hofstetter H,Wolf RM,Seuwen K||Nature (425:93)||2003|