Positive Control: Jurkat, Raji, NCI-H929
Predicted Reactivity: Mouse (85%), Rat (80%), Dog (89%), Rhesus Monkey (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis inhibitor 1; baculoviral IAP repeat-containing 2; Baculoviral IAP repeat-containing protein 2; C-IAP1; Cellular inhibitor of apoptosis 1; hIAP-2; IAP homolog B; IAP-2; Inhibitor of apoptosis protein 2; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2
Gene Aliases: API1; BIRC2; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
UniProt ID: (Human) Q13490
Entrez Gene ID: (Human) 329