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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated, corresponding to the C-terminal domain of human delta-1 Opioid Receptor.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24532 detects Opioid Receptor, Delta 1 in human samples. Peptide sequence identity/similarity to mouse:81/87%. Rat 75/75%.
PA1-24532 has been successfully used in immunohistochemistry (formalin-fixed paraffin-embedded sections) procedures.
The PA1-24532 immunogen is a synthetic peptide, KLH conjugated, corresponding to the C-terminal domain of human delta-1 Opioid Receptor. Sequence identity/similarity to Mouse: 81/87%. Rat: 75/75%.
Store at 4°C short term. For extended storage, store at -20°C, avoiding freeze/thaw cycles.
OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimerâ•?s patients and in the putamen in Parkinsonâ•?s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
D-OR-1; delta opioid receptor 1; DOR-1; opioid receptor, delta 1