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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human dopamine receptor D4|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28756 targets dopamine receptor D4 in WB applications and shows reactivity with Human samples.
The PA5-28756 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human dopamine receptor D4.
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
D(2C) dopamine receptor; D(4) dopamine receptor; D4DR; dopamine D4 receptor; dopamine receptor 4; seven transmembrane helix receptor
AW125663; D4DR; D4R; Drd-4; DRD4