MA1-079 has been successfully used in Western blot, immunohistochemistry, immunocytochemisty and immunofluorescent applications and reacts with human, monkey, and rat samples.
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EIF-2; eIF-2-alpha; EIF-2A; EIF-2alpha; EIF2; EIF2A; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Gene Aliases: EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A; EIF2S1