EIF4E2 is expressed exclusively in the cytoplasm. This protein recognizes and binds the 7 methylguanosine containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
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Protein Aliases: eIF-4E type 2; eIF4E type 2; eIF4E-like cap-binding protein; eIF4E-like protein 4E-LP; EIF4E2; EIF4EL3; Eukaryotic translation initiation factor 4E homologous protein; Eukaryotic translation initiation factor 4E type 2; Eukaryotic translation initiation factor 4E-like 3; h4EHP; mRNA cap-binding protein 4EHP; mRNA cap-binding protein type 3
Gene Aliases: 4E-LP; 4EHP; EIF4E2; EIF4EL3; IF4e
UniProt ID: (Human) O60573
Entrez Gene ID: (Human) 9470