Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
The gamma-tubulin (TUBG1; relative molecular weight about 48 kDa) is a minor member of tubulin family (less that 0.01% of tubulin dimer). The gamma-tubulin ring structures, however, serve to provide structural primer for initiation of microtubular nucleation and growth, thereby being crutial for microtubule-based cellular processes, above all for mitotic spindle formation. In animal cells, a center of microtubule organization is the centrosome composed of a pair of cylindrical centrioles surrounded by fibrous pericentriolar material containing gamma-tubulin. Formation of the mitotic spindle is preceded by duplication of centrosome during S phase. Before mitosis, both centrosomes increase their microtubule nucleation capacity and form two microtuble asters that are pushed apart from each other by the forces of motor proteins associated at the microtubule surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-Jun N-terminal kinase 2; gamma tubulin; Gamma-1-tubulin; Gamma-2-tubulin; Gamma-tubulin complex component 1; GCP-1; JNK/SAPK alpha; Jun kinase; MAP kinase 9; MAPK 9; mitogen activated protein kinase 9; Mitogen-activated protein kinase 9; p54-alpha; protein kinase, mitogen-activated 9; SAPK-alpha; stress activated protein kinase alpha II; Stress-activated protein kinase JNK2; Tubulin gamma-1 chain; Tubulin gamma-2 chain; tubulin, gamma 1; tubulin, gamma 2; tubulin, gamma polypeptide
Gene Aliases: 1500010O08Rik; AI451582; AI503389; AI504772; AI851083; BOS_19123; BOS_19126; CDCBM4; GCP-1; JNK2; Mapk9; p54aSAPK; Prkm9; SAPK; TUBG; TUBG1; TUBG2; TUBGCP1; Tubgl
Entrez Gene ID: (Rat) 50658, (Mouse) 26420, (Human) 7283, (Bovine) 541101, (Dog) 403695, (Bovine) 540216, (Human) 27175, (Mouse) 103733, (Chinese hamster) 100759432, (Rat) 252921, (Rat) 680991, (Mouse) 103768