The MA1-850-A647 immunogen is a recombinant protein containing residues A A T R P D Y I S W G T Q E Q of human gamma Tubulin.
Gamma Tubulin is required for structure and function in microtubule growing centers. Disruption of gamma Tubulin has also shown to cause mitotic arrest and a sharp decrease in microtubule quantity. This disruption also causes mutations in the microtubule organizing centers never seen in wild-type cells. gamma Tubulin is exclusively localized to the spindle poles in animal cells. Localization and timing of gamma Tubulin during cell cycle is thought to be highly regulated.
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Protein Aliases: Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; TUBG; TUBGCP1; Tubulin gamma-1 chain; tubulin, gamma 1; tubulin, gamma polypeptide
Gene Aliases: CDCBM4; GCP-1; TUBG; TUBG1; TUBGCP1
UniProt ID: (Human) P23258
Entrez Gene ID: (Human) 7283