|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptides rcorresponding to residues M(1) F Q L P V N(7) C K(1096) L S S Q Q A(1102) of the N- and C-termini of human ADNP.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4223 detects the hADNP protein in human samples.
PA1-4223 has been successfully used in Western blot procedures.
The PA1-4223 immunogen is a synthetic peptides rcorresponding to residues M(1) F Q L P V N(7) C K(1096) L S S Q Q A(1102) of the N- and C-termini of human ADNP, separated by a cysteine.
The activity-dependent neuroprotective protein (hADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. hADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. hADNP is implicated in maintaining cell survival, perhaps through modulation of p53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.