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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:5,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:500 | - |
Immunocytochemistry (ICC/IF) |
1:400 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1E12A7 |
Immunogen |
hIST1 Fusion Protein Ag28364 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1000 µg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Aliquoting is unnecessary for -20°C storage.
Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hIST1; increased sodium tolerance 1 homolog; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; MAPK activating protein PM28; MGC117220; overexpressed in lung cancer 1; pm28; Putative MAPK-activating protein PM28
Gene Aliases: 2400003C14Rik; AW536298; IST1; KIAA0174; mKIAA0174; OLC1; RGD1307799
UniProt ID: (Human) P53990, (Rat) Q568Z6, (Mouse) Q9CX00
Entrez Gene ID: (Human) 9798, (Rat) 307833, (Mouse) 71955
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