|ChIP assay (ChIP)||Assay-dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 8 and 170 of Human hnRNP A/B|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27549 targets hnRNP A/B in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27549 immunogen is recombinant fragment corresponding to a region within amino acids 8 and 170 of Human hnRNP A/B.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABBP-1; ABBP1; apobec-1 binding protein 1; APOBEC1-binding protein 1; apolipoprotein B mRNA editing enzyme; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1; catalytic polypeptide 1-binding protein 1; Heterogeneous nuclear ribonucleoprotein A/B; hnRNP A/B; hnRNP type A/B protein; HNRPAB
Gene Aliases: ABBP1; HNRNPAB; HNRPAB
UniProt ID: (Human) Q99729
Entrez Gene ID: (Human) 3182
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