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QED Bioscience

mGluR1/5 Glutamate Receptor Monoclonal Antibody (S75-33)

View all (22) mGluR1/mGluR5 antibodies

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mGluR1/5 Glutamate Receptor Monoclonal Antibody (S75-33)

Product Details

56526-100UG

Applications
Tested Dilution
Publications

Western Blot (WB)

1-2 µg/mL
-

Immunohistochemistry (IHC)

1-5 µg/mL
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

S75-33

Immunogen

Fusion protein corresponding to aa 824-1203 (cytoplasmic C-terminus) of rat mGluR5b (accession no. NP_058708.1).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

may play a role in synaptic transmission; may interact with mGluR1, another group I metabotropic glutamate receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: G protein coupled receptor family C group 1 member A; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member E; glutamate receptor; glutamate receptor, metabotropic 1; glutamate receptor, metabotropic 5; GPCR family C; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5 homolog; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; mGluR1; mGluR5; mGluR5f; mGluR5g; mGluR5h; mGluR5i; mGlurR1a; protein phosphatase 1, regulatory subunit 85; protein phosphatase 1, regulatory subunit 86; unnamed protein product; variant b of mGluR5

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Gene Aliases: 4930455H15Rik; 6430542K11Rik; Glu5R; Gm10828; GPRC1A; GPRC1E; MGLU1; mGlu5; MGLUR1; MGLUR5; mGluR5b; nmf373; PPP1R85; PPP1R86; rcw; SCA44; SCAR13; wobl

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UniProt ID: (Human) Q13255, (Human) P41594, (Rat) P23385, (Mouse) P97772, (Rat) P31424, (Mouse) Q3UVX5

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Entrez Gene ID: (Human) 2911, (Human) 2915, (Rat) 24414, (Mouse) 14816, (Rat) 24418, (Mouse) 108071

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Function(s)
adenylate cyclase inhibiting G-protein coupled glutamate receptor activity G-protein coupled receptor activity protein binding glutamate receptor activity G protein-coupled neurotransmitter receptor activity G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential protein tyrosine kinase activator activity A2A adenosine receptor binding identical protein binding protein tyrosine kinase binding PLC activating G-protein coupled glutamate receptor activity fibronectin binding collagen binding estrogen receptor binding laminin binding protein sequestering activity calmodulin binding PDZ domain binding
Process(es)
G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled glutamate receptor signaling pathway G-protein coupled glutamate receptor signaling pathway chemical synaptic transmission locomotory behavior sensory perception of pain regulation of membrane potential positive regulation of MAPK cascade regulation of sensory perception of pain regulation of synaptic transmission, glutamatergic regulation of postsynaptic membrane potential synaptic signaling via neuropeptide temperature homeostasis response to amphetamine desensitization of G-protein coupled receptor protein signaling pathway regulation of transcription, DNA-templated positive regulation of cytosolic calcium ion concentration learning or memory associative learning positive regulation of dopamine secretion operant conditioning protein targeting to nuclear inner membrane response to morphine response to ethanol response to antibiotic positive regulation of long-term neuronal synaptic plasticity synapse organization positive regulation of calcium-mediated signaling cognition response to corticosterone negative regulation of dendritic spine morphogenesis sensory perception of hot stimulus negative regulation of excitatory postsynaptic potential positive regulation of cellular response to hypoxia regulation of long term synaptic depression positive regulation of intracellular signal transduction positive regulation of sensory perception of pain cellular response to beta-amyloid conditioned place preference positive regulation of neural precursor cell proliferation protein phosphorylation learning phosphatidylinositol-mediated signaling regulation of long-term neuronal synaptic plasticity modulation of synaptic transmission regulation of glutamate secretion calcium-mediated signaling positive regulation of cell migration negative regulation of viral entry into host cell receptor-mediated virion attachment to host cell membrane depolarization synaptic transmission, GABAergic cellular response to electrical stimulus L-glutamate import across plasma membrane negative regulation of protein localization to plasma membrane
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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