|Tested species reactivity||Hamster|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Colchicine-resistant viable Chinese Hamster Ovary (CHO) cells, followed by purified P170 glycoprotein from CHO cells|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12619 targets p170 in FACS, IF, IHC (F), and WB applications and shows reactivity with Hamster samples.
The MA5-12619 immunogen is colchicine-resistant viable Chinese Hamster Ovary (CHO) cells, followed by purified P170 glycoprotein from CHO cells.
Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.