|ChIP assay (ChIP)||1:100|
|Immunoprecipitation (IP)||Assay Dependent|
|Immunoprecipitation (IP)||See 1 publications below|
|Species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||1038-1161 of 2414 of EP300 Protein.|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
730044 has been successfully used in ChIP analysis of p300 in mouse kidney.
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E1A-associated protein p300; E1A-binding protein, 300kD; EP300; Histone acetyltransferase p300; KAT3B; p300 HAT
Gene Aliases: A430090G16; A730011L11; EP300; KAT3B; P300; p300 HAT; RSTS2
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