|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:100|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 8 publications below|
|Immunoprecipitation (IP)||See 2 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Rabbit , Mouse , Human|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Immunogen||Recombinant, full-length human p38 beta-2; the product of the p38-beta gene|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
33-8700 has been successfully used in immunofluorescence and western blot.
33-8700 specifically recognizes the beta isoform of p38, with slight reactivity to p38-gamma.
MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAP kinase 11; MAP kinase p38 beta; MAPK 11; mitogen activated protein kinase 11; Mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; p38-2; P38B; p38Beta; P38BETA2; PRKM11; protein kinase, mitogen activated kinase, 11, p38beta; SAPK2; SAPK2B; stress-activated protein kina; stress-activated protein kinase 2; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b
Gene Aliases: MAPK11; p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
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