|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 334-366 amino acids from the center region of human MAPK11|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.