|Tested species reactivity||Human, Primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues around the carboxy terminus of p38ß MAPK|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other isoforms of p38 MAPK.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (NhpKs), preferably by NhpK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
MAP kinase 11; MAP kinase p38 beta; MAPK 11; mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; OTTHUMP00000196655; stress-activated protein kinase 2; stress-activated protein kinase-2; stress-activated protein kinase-2b
MAPK11; p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B